Some of the OBS 3/4 trucks and vans (what rhyme or reason vs the 8 bolt semi? no idea.. looks like most or all gear ratios were available with either hub). Vans are the same width as 4x4 trucks, but spring perches are different width, 4x2 trucks the axle itself is 3" skinnier (as long as you're swapping from 4x4 or 4x2 to the same, the width is the same between 10 and 14 bolt). From the research I did, the only differences (provided you have the 11" drums on your 10 bolt, 10" is an option as well on the 10 bolt) is the u-joint size.. and local auto parts stores stock the conversion joint from 1330 to 1350...
However, the guy I was going to buy the 14 bolt from wants to keep it with the front diff (for $400, not a bad price), but hes also got a 10 bolt locker in the ratio I need for $150. So... $150 to have my truck back running it will be. Upgrades maybe some day?
My truck is essentially a 3/4 ton 2 door suburban (even has the bumper cutouts), with 1/2 ton axles and springs.
So... yes.